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Combined Blockage of E-selectin and CXCR4 (GMI-1359) Enhances Anti-Leukemia Effect of FLT3 Inhibition (Sorafenib) and Protects Hematopoiesis in Pre-Clinical AML Models
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Normal cells typically regulate cholesterol levels through SREBP2 [42], but tumor cells may have lost this self-regulation mechanism
