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These findings have also been shown in animal models, both in mice and in guinea pigs, where vitamin C supplementation, both general and during OVA sensitization, strongly reduced AHR [283]

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This eliminates IGF-1 elevation as a confounding variable in metabolic study designs a critical advantage when the objective is to investigate lipolytic pathway activity in isolation from the anabolic, mitogenic, and glucose-modulating effects associated with full-length hGH

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