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Adverse effects observed in trials include nausea, vomiting, gallbladder disease, dehydration, and potential pancreatitis

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(114) reported that pain severity, functional disability scales, photophobia, phonophobia, and nausea were significantly reduced in patients with menstrual migraine after taking vitamin E supplements (400 units daily for 5 days, starting 2 days before to 3 days after menstruation for two cycles) (114)

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