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Removal or destruction of the stomach Vitamin B12 deficiency can develop in people who have had surgery to remove part or all of the stomach
62 Central sensitization, the perception of pain and therapeutic efficacy of pain relieving drug and/or treatments are commonly tested and evaluated in painrelated animal behavior
204 In addition, in a placebo-controlled crossover trial in 22 men between 50 and 69 years of age with DHEA-S levels below 150 mcg/dL, 50 mg of DHEA per day for four months did not improve body composition

This profile supports its application in research focused on alternative pain signaling mechanisms, including interactions with endogenous opioid peptides and neurochemical mediators such as substance P
