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Sanz AB, Sanchez-Nio MD, Ramos AM, Moreno JA, Santamaria B, Ruiz-Ortega M, et al
Mechanisms of Resistance to PD-1 and PD-L1 Blockade
GPX4 is involved in the regulation of cell death including ferroptosis [22], and together with GPX5, in male fertility [23,27].The functions of GPX6 are less well known, but recently it has been implicated as modulator of Huntingtons disease [13,28]
Accordingly, the 2 effectors cause tissue growth by first creating newly differentiated cells and then promoting their multiplication
