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Description
Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

Receptor engagement is associated with adenylate cyclase activation and elevations in intracellular cyclic AMP

Furthermore, several sigma-2 receptor ligands are under investigation, including CT1812, rivastigmine and SAS0132

[DOI] [PubMed] [Google Scholar] [20].Poole LB, The basics of thiols and cysteines in redox biology and chemistry, Free Radic
