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Evolution of Translational Omics: Lessons Learned and the Path Forward (National Academies Press, 2012)

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hydrogen peroxide (Alikhan et al.) is produced as a byproduct, and catalase and glutathione peroxidase eliminate it

In the untreated intoxicated group, there was extensive infiltration of neutrophil polymorphs within the interstitial and tubular regions, accompanied by tubular dilation and deposition of brown amorphous substances, indicative of crystal-induced inflammation