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Vitamin B12 and One-Carbon Metabolism Vitamin B12 (cobalamin) is an essential cofactor for several enzymes involved in one-carbon metabolism and energy-related pathways: Methionine Synthase: B12-dependent remethylation of homocysteine to methionine is central to the generation of S-adenosylmethionine (SAM), a universal methyl donor used in DNA, protein, and phospholipid methylation
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association
PMID 23936513
[DOI] [PubMed] [Google Scholar] 51.Ogita H, Liao J
