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Signal transducers and activators of transcription (STATs) act as substrates for JAKs and function as transcription factors
Although being a simple chemical modification, sulfenic acid formation can have a dramatic effect on protein function [130, 137, 144]
Together, the lack of cysteine and GSH cause an elevation of ROS, which prevents the stress response elicited by ATF4 in a vicious cycle, which mediates cell death
