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[PubMed Citation] The pharmacokinetics after oral administration of 200, 600 or 1200 mg of N-acetylcysteine (NAC) were studied in 10 healthy subjects
The GCDH gene is located on chromosome 19p13.13 and is composed of 12 exons that generate two alternatively spliced mRNAs, both of which encode distinct precursor proteins, isoform a is 438 amino acids and isoform b is 428 amino acids, The isoform b protein is not functional as a glutaryl-CoA dehydrogenase
Gunasekara P, Hettiarachchi M, Liyanage C, Lekamwasam S
doi:10.1186/s10194-015-0547-z Radtke A, Lempert T, Gresty MA, Brookes GB, Bronstein AM, Neuhauser H
