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Researchers have employed a high-fat diet to induce a NAFLD model in APOE / mice, revealing that testosterone deficiency can exacerbate hepatic iron deposition in hepatocytes by modulating BMAL1 [267]
Antioxidants (Basel, Switzerland) , 10(2), 174
Well-designed epidemiologic studies are still needed to determine whether other epigenetic changes precede the development of SARD and whether such changes could be modified to abrogate disease
