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Posterior subcapsular cataracts are often associated with more rapid progression compared to nuclear or cortical cataracts, and they tend to cause significant symptoms at earlier stages due to their central location within the visual axis, which interferes with both distance and near vision

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Our study thus highlights how long-range eIF2B allostery can be pharmacologically manipulated to sustain or attenuate the ISR

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G.Prez-TorradoR.BarrioE.et al

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