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Cellular senescence is closely linked to fibrosis, as demonstrated by nonproliferative, p16-positive myofibroblasts in fibrotic lung tissues [15]
Cancer Res 67:876880 Rusiecki JA, Baccarelli A, Bollati V, Tarantini L, Moore LE, Bonefeld-Jorgensen EC (2008) Global DNA hypomethylation is associated with high serum-persistent organic pollutants in Greenlandic Inuit
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Additionally, specific antidiabetic medications, such as metformin, TZD, and glucagonlike peptide1 (GLP1) agonists, may exert a dual effect by regulating glucose levels and reducing inflammation (Figure 2)
