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5.3.2 Development of novel drugs Mitochondrial dysfunction is a central pathological feature of DCM, and developing drugs that restore mitochondrial function holds significant therapeutic potential (198)

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BB is a major gut microbiota metabolite of l-carnitine, and TMA formation from BB is influenced by dietary habits

ACO1 expression appears to be strongest in the pericarp, septa and columella of orange to red fruit, matching the tissue-specific ACO in vitro activity reported by Van de Poel et al