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In order to compare the three different assays, we used the established rat model of angiotensin-II-induced hypertension that was previously fully characterized regarding the increased blood pressure, impaired vascular function and aggravated inflammation as well as oxidative stress, including uncoupling of endothelial nitric oxide synthase, crosstalk of phagocytic NADPH oxidase with mitochondrial ROS formation [Citation2224], and the central role of myelomonocytic cells [Citation25]

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J Alzheimers Dis 44(4):12911302 Huynh T-PV, Davis AA, Ulrich JD, Holtzman DM (2017) Apolipoprotein E and Alzheimers disease: the influence of apolipoprotein E on amyloid- and other amyloidogenic proteins