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Samples were diluted to 2 M urea with 50 mM ammonium bicarbonate
Combined dosing increases total peptide load and may alter the risk profile, particularly regarding interactions with other therapies

XENical in the prevention of diabetes in obese subjects (XENDOS) study a randomized study of orlistat as an adjunct to lifestyle changes for the prevention of type 2 diabetes in obese patients
doi: 10.1134/S0006297917040149
