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Continuous use makes sense for users still experiencing ongoing improvements without plateau suggesting continued benefit from sustained application, highly satisfied with current results wanting to maintain peak benefits without decline risk, financially comfortable with indefinite product investment as skincare priority, psychologically comfortable with long-term commitment to effective treatment, experiencing rapid benefit decline during previous break attempts indicating necessity of ongoing application, and prioritizing maximum results over cost optimization or flexibility concerns

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REDEFINE 1 (Phase 3a, NEJM 2025) Garvey et al., n=3,417, 68 weeks

Physiological and Immunological Status of Adult Honeybees (Apis mellifera) Fed Sugar Syrup Supplemented with Pentadecapeptide BPC 157