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Neutrophil extracellular traps have also an important role in sepsis-induced endothelial dysfunction, causing the expression of adhesion molecules, participating in the prothrombotic state by increasing platelet adhesion on the ECs surface, and contributing to thrombin-mediated fibrin generation (110, 111)

It is worth noting that a diminished GSH level was observed in rats fed with a Se-deficient diet

To provide a comprehensive overview of the current state and future directions of GO research, Table 9 systematically summarizes the key mechanisms, performance metrics, remaining challenges, and future research directions for each application domain discussed in this review

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