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We proceeded to test whether any of the AR-mediated PGx-eQTL SNPs might contribute to BC prognosis and/or endocrine therapeutic response by examining the association of these PGx-eQTL SNPs with BC phenotypes from three genome-wide association studies (GWAS) that we have published: (1) The National Surgical Adjuvant Breast and Bowel Project (NSABP) is a clinical trial of SERMs (tamoxifen or raloxifene) in the reduction of risk for developing breast cancer in women at increased risk of the disease [2]
Baraban SC, Taylor MR, Castro PA, Baier H
These data suggest that LMP formulation increases in serum bioavailability of creatine is species-independent
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