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About one-third of participants experienced nausea or diarrhea, and about one-quarter developed constipation

N Engl J Med 389(24):22212232

Research Citations Finan B, Ma T, Ottaway N, et al

Importantly, these effects occur in a glucose-dependent manner, reducing the risk of severe hypoglycemia when using incretin hormones or their synthetic counterparts, like GLP-1 and GIP receptor agonists, without other diabetes medications
