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The transcription factor cJun has been shown to regulate glial phagocytosis of axonal debris through activation of the draper protein in Drosophila melanogaster (MacDonald et al., 2013), autophagy and cell death through the regulation of pro and antiapoptotic proteins Bcl2 associated Xprotein (Bax), Bcell lymphoma 2 (Bcl2) (Bogoyevitch et al., 2010)
Age-induced alterations of granulopoiesis generate atypical neutrophils that aggravate stroke pathology
