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Additionally, the elevated insulin will increase D2 activity and suppress TSH levels, further decreasing thyroid levels and making it inappropriate to use the TSH as a reliable marker for tissue thyroid levels in the presence of elevated insulin levels as occurs with obesity, insulin resistance, or type II diabetes
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Indeed, hyperglycemia induces the production of reactive oxygen and nitrogen species, and the resulting oxidation of lipids, proteins, and DNA mediates diabetic complications such as neuropathy, nephropathy, retinopathy, and vascular damage
A neuro-immune model of Myalgic Encephalomyelitis/Chronic fatigue syndrome
