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While receptor degradation allows for termination of signaling, recycling back to the plasma membrane is a mechanism for sustained signaling

Constitutive expression of ErbB-2 in gallbladder epithelium results in development of adenocarcinoma

Zare, R.N

In terms of mechanism, this study demonstrated that GSTP1 and STAT3 could form a complex, and GSTP1 upregulation leads to the activation of the STAT3 pathway
