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For this reason, these proteins represent potential targets for anti-cancer therapy and should be added to the existing list, including sugar and amino acid transporters, which are already considered druggable targets

Apo A1 synthesised in the liver together with that released spontaneously from chylomicrons is a key molecule that binds to phospholipids with a little cholesterol of cellular origin, and it has been described as the scaffold for HDL assembly and is secreted as pro-apo A1, which is rapidly cleaved by a circulating metalloproteinase to generate the mature polypeptide

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