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Description
These studies involved a broad range of cancer cells, parasites, and their derivatives conducted in vitro and in vivo

Collectively, these mechanisms may convert transient peripheral inflammation into a self-sustaining chronic inflammatory state within the central nervous system, ultimately manifesting as delayed fatigue, reduced attention, and cognitive impairment observed in PEM patients following physical or cognitive exertion (134, 135)

2 and 3), which seems to be inconsistent with the previously defined role of Glu as a critical wound signal that activates plant defense response 11

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