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Masgras I, Cannino G, Ciscato F, Sanchez-Martin C, Pizzi M, Menga A, et al
Among the Nrf2 inhibitors, metformin, isoorientin, wogonin, trigonelline, and sulfasalazine have shown antitumor activity by downregulating Nrf2 through diverse mechanisms ( Figure 3 )
fowleri adapts to copper-deprived conditions by upregulation of NDH-2
Clinical data on PD are still lacking
