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We establish that CstB self- S -sulfonates C201 in a thiol persulfide, Fe(II) and O 2 -dependent manner, which is then shuttled to a persulfidated C408 in the rhodanese domain 27 away via electrostatic steering to generate thiosulfate as the sole oxidation product
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Synaptic biomarkers, or proteins found in cerebral spinal fluid, have been found to be linked to early indicators of Alzheimer's disease progression in a study that observed over 700 people: Biomarkers linked to excitatory neuron communication, specifically Neuronal Pentraxin (NPTX2), were observed at low levels to determine correlation

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