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Previous studies reported that WAGO-1 is P granule-associated and represses transcripts that have been primed by the piRNA pathway as part of the secondary RNAi response 47

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EMBO J 21:665674 Coburn C, Allman E, Mahanti P, Benedetto A, Cabreiro F, Pincus Z, Matthijssens F, Araiz C, Mandel A, Vlachos M, Edwards SA, Fischer G, Davidson A, Pryor RE, Stevens A, Slack FJ, Tavernarakis N, Braeckman BP, Schroeder FC, Nehrke K, Gems D (2013) Anthranilate fluorescence marks a calcium-propagated necrotic wave that promotes organismal death in C elegans

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