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Since mice constitutively expressing a GPX4 cys/cys variant are not viable when kept on a congenic background [72], these data point to a crucial role for full GPX4 activity during embryogenesis, whereas residual activity might be sufficient to prevent tubular injury under steady-state conditions
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[DOI] [PMC free article] [PubMed] [Google Scholar] 94.Qin L., Ma K., Wang Z.J., Hu Z., Matas E., Wei J., Yan Z
