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Exome-wide association study of treatment-resistant depression suggests novel treatment targets
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At 24 h, eloralintide and cagrilintide had comparable ED 50s , and at 96 h, eloralintide had a significantly lower ED 50 than cagrilintide for changes from baseline in food intake (ED 50 : 3.7 nmol/kg [SE: 1.1] vs 8.5 nmol/kg [SE: 1.2]) but not body weight (ED 50 : 6.1 nmol/kg [SE: 1.2] vs 11.4 nmol/kg [SE: 1.3]), which suggests that the PK of a single dose of eloralintide (Table S6
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