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Description
Our animal models, induced using endothelin-1 (ET-1), reflect clinically relevant cerebral I/R conditions yet may not fully capture the complexity of human pathophysiology, including inter-individual anatomical variation and comorbidities ( in vivo , including their potential off-target effects and clearance pathways
The tumor suppressor Hic1 maintains chromosomal stability independent of Tp53
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Therefore, the research and development of safer and more efficient synthetic antioxidants remains an important direction for research
