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Ng CH, Tan DJH, Lim XC, Yong JN, Syn N, Soon GST, Huang DQ, Xiao J, Lim GEH, Lim WH, Tan EXX, Dan YY, Noureddin M, Siddiqui MS, Muthiah MD (2022) A diagnostic test meta-analysis evaluating imaging-based and blood biomarker-based assessment tools for fibrosis after liver transplantation

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Studies using constant light to decrease melatonin production show it causes Alzheimer s-like damage in the cells along with increasing the need for antioxidants such as SOD and monoamine oxidase.[ref] There have been quite a few recent studies and reviews pointing to the role of both low melatonin and circadian disruption in the accumulation of amyloid-beta plaque.[ref] So what are the results of human studies that have used long-term melatonin supplementation to prevent Alzheimers disease