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Deficiency can lead to macrocytic anaemia, neurological symptoms including peripheral neuropathy, cognitive changes, and fatigue

National Kidney Disease Education Program

Later studies confirmed even larger increases (up to 100%) when arterialized blood (rather than venous blood) was sampled (246, 247)

doi: 10.1007/s11136-014-0705-9 582 DevendorfARJacksonCTSunnquistM
