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FrosstPBlomHJMilosRGoyettePSheppardCAMatthewsRGet al

These findings collectively demonstrate that exercise training facilitates collateral vessel formation through multiple mechanisms, including miRNA expression regulation and local inflammatory response modulation

2024;10(19) doi: 10.1016/j.heliyon.2024.e38758

Molecular docking simulations and the antagonistic effect of spironolactone (SPI) in their study suggested that the Takeda G protein-coupled receptor 5 (TGR5/GPBAR1) might mediate these effects of iso-LCA on NK cells, although direct functional validation is pending (44)
