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Contraindications include pregnancy, active malignancy, and autoimmune disorders under immunosuppressive therapy

Kumar G, Adhikrao PA
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CagriSema combines two proven mechanisms (amylin + GLP-1) in a fixed-dose injection, achieving 20.4% weight loss in Phase 3, with an NDA already filed and the advantage of building on the well-characterized semaglutide platform

Lancet 386 , 376387 (2015)
