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Because the induction of these genes is only transient, the glutamate consumption is likely to be buffered by steady-state central carbon metabolism, under which glucose and glutamate fuel mitochondria to support cellular bioenergetic demands (Fig

Haase H, Ober-Blobaum JL, Engelhardt G, Hebel S, Heit A, Heine H, et al

Particularly, it determined the upregulation of ROS-scavenging enzymes, anti-inflammatory cytokines, (IL-10, IL-6 and PPAR ), tight junctions proteins, such as ZO-1, MUC-2, claudin-3, and the downregulation of inflammatory genes (TNF-, IL-1) [14]

Handling & Use Conditions Handle sealed oral research format units with standard laboratory PPE