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Supplementary Material 2: Additional file 2.pdf contains the figure: Immunohistofluorescence analysis of claudin-1 and claudin-2 localization in the brain of control, vehicle-treated/CDNB perfused and DMF-treated/CDNB perfused 3-day-old rats

Supports Brain Function: Some studies suggest that B P C-157 can help protect neurons and potentially assist in cognitive health and recovery from traumatic brain injuries

In this situation compounds blocking VEGF or inhibitors of the Tyrosine kinases, blocking the activation of receptors like VEGFR2 , can be effective

This places BPC-157 in a unique category as a broad-spectrum neuromodulator rather than a simple neuroprotectant (Sikiric et al., 2014)