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This lipolytic effect appears to be mediated through activation of 3-adrenergic receptors on adipocytes, which are G-protein coupled receptors that, when activated, stimulate adenylyl cyclase to increase intracellular cAMP levels
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Apoptotic signaling, oxidative stress, and mtDNA damage collectively exacerbate neuroinflammation and neurodegeneration (McGovern and Barreto, 2021) propagation in the long term (De Gaetano et al., 2021
