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Moreover, research indicates that reduced vitamin K 2 levels resulting from antibiotic-induced microbiota depletion are associated with decreased osteocalcin and bone strength in mice (196)
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The findings supported the VKA-renal calcification hypothesis suggesting that VKA use may accelerate vascular calcification in the renal microvasculature, leading to the progression of CKD
Li DY, Smith DG, Hardel R et al (2013) Melatonin receptor genes in vertebrates
