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Leng A, Feldon J, Ferger B
AKG in malignant gliomas In gliomas, the effects of AKG are highly context-dependent, varying according to IDH mutation status, amino acid metabolism, and nutrient availability
52 Further, the safety and tolerability of MSCs as a treatment for AD have been shown in a phase 1 clinical trial
however, this phenomenon is accompanied by a continuous release of glutamate and substance P onto the second-order neurons, alongside diminished central levels of opioid peptides and serotonin [139,140]
