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PMID: 40892544 Sci Data High-throughput drug screening identifies novel therapeutics for Low Grade Serous Ovarian Carcinoma

doi: 10.3390/ijms23042032 170 FariaRSantanaMMAveleiraCASimesCMacielEMeloTet al

The trigger is the combination of rapid weight loss and caloric restriction: when appetite suppression is working well, patients are eating significantly less, and if protein and micronutrient intake fall below what the body needs, hair follicles are among the first structures deprioritized

This negligence triggers the skins natural defense mechanism, resulting in the overproduction of melanina brown pigment that leads to skin darkening