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Description
The lead candidate 37 (HFI-419) exhibits brain exposure following intravenous administration in rats but was found to be rapidly degraded to the corresponding deacetylated and less active IRAP inhibitor (Mountford et al., 2014)
Se utiliza ampliamente en modelos de investigacin celular y bioqumica
P values are calculated using unpaired, two-tailed t-tests
15) and metformin (direct inhibitor of CI) 323 (1:1
