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Fusion primers with dual-indexed PCR adapters were used to generate the construct library, and short fragments were removed with AMPure beads

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Oral treatment of vitamin B12 deficiency
In addition to oligonucleotide therapeutics, some small-molecule NNMT inhibitors have been reported recently [5659] and several have shown effectiveness in the prevention or treatment of obesity and T2D in vitro [60, 61] or in preclinical animal models [10, 58, 62], validating NNMT as a pharmacological drug target
