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A phase 1 study of pegylated recombinant arginase (PEG-BCT-100) in combination with systemic chemotherapy (capecitabine and oxaliplatin)[PACOX] in advanced hepatocellular carcinoma patients
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These changes facilitated the recruitment and activation of macrophages and myofibroblast-like cells in the liver, leading to increased collagen deposition and the progression of liver fibrosis
