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Description
Both MPH and amphetamines act by blocking presynaptic dopamine (DA) and norepinephrine (NE) transporters, thus increasing catecholamine transmission

Interestingly, the reduction of IGF-1 was observed irrespective of the weight loss, suggesting that IGF-1 downregulation precedes cachexia development

There is no standardized cycle recognized by regulatory agencies

Reference Hu, Yao, Cai, Pan, Liu and Bai2020
