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Using advanced neuroimaging techniques, his team demonstrated that patients with ME/CFS have significantly depleted levels of cortical glutathione compared to healthy controls
Therefore, those studies suggest that ASCT2 expression can be a marker of ferroptosis sensitivity
These findings underscore the key role of ALDH2 in mitigating harmful effects of 4-HNE accumulation in IRI in various tissues and organs
doi: 10.1016/j.cell.2020.02.058
