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Deficiency of eNOS can result in endothelial dysfunction leading to diabetic nephropathy

The importance of the biliary excretion system is underscored by experiments in which 1-naphthylisothiocyanate (ANIT) was administered to experimental animals

originally called FKHRL1) that has pro-apoptotic activity

It has also been shown to improve cognitive function in animal models of Alzheimers disease