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It was found that the anti-atherosclerotic effect of berberine was associated with the stimulation of Akkermansia in ApoE -/- mice ( Fecal microbiota transplantation (FMT) is a promising method of introducing healthy bacteria from healthy subjects into the gastrointestinal tract of patients with dysfunctional guts, which has received much attention in recent years ( Although gut microbiota-targeted therapy to treat CVD is promising in the context of increasing positive experimental and clinical evidence, discrepant results have also been reported in both experimental and clinical studies
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