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FDA Status: Not evaluated or approved by the U.S
This observation aligns with previous work showing that pharmacological inhibition or genetic ablation of NMDA receptors in agouti-related-protein (AgRP)-expressing neurons alters synaptic adaptation to fasting 39,40
Treating obese mice twice a day for a month caused them to gain 10 times less fat than untreated mice and lose 12% of their body weight
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