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Several ferroptosis-associated genes, including ACSL4, acyl-CoA synthetase family member 2, GPX4, LPCAT3, NCOA4, solute carrier family 38, member 1 (SLC38A1) and glucose-6-phosphate dehydrogenase, all of which participate in the regulation of lipid or iron metabolism (10,67), have been shown to be markedly dysregulated (downregulated or upregulated) in UC specimens (5)

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Ao contrrio dos medicamentos aprovados, eles no passaram pelos testes rigorosos necessrios para compreender seu perfil de segurana em seres humanos